Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 16/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25237844 | 1.00 | OPRK1 (0.41) | OPRK1PDE5ACHEK1PDE4APDE4B | |
| SCHEMBL23012453 | 0.89 | OPRK1 (0.41) | OPRK1PDE5A | |
| SCHEMBL25284971 | 0.84 | PDE5A (0.40) | OPRK1PDE5ACHEK1PDE4APDE4B | |
| SCHEMBL31208551 | 0.84 | PDE5A (0.40) | OPRK1PDE5ACHEK1PDE4APDE4B | |
| SCHEMBL18339703 | 0.82 | KDM4E (0.46) | — | |
| SCHEMBL22835084 | 0.78 | TRPC6 (0.47) | OPRK1PDE5ACHEK1PDE4APDE4B | |
| SCHEMBL29598236 | 0.78 | TRPC6 (0.47) | OPRK1PDE5ACHEK1PDE4APDE4B | |
| SCHEMBL31208501 | 0.77 | OPRK1 (0.42) | OPRK1 | |
| SCHEMBL20563399 | 0.77 | NR4A2 (0.48) | PDE5A | |
| SCHEMBL23012559 | 0.76 | KMO (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742542-A | Inhibitors of MET kinase | 金耐特生物制药公司 | 2024-10-01 | — | — | CN | disclosed |