Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 1.00 |
| ▸ | CA1 | P00915 | 5/20 | 0.73 |
| ▸ | CA2 | P00918 | 5/20 | 0.73 |
| ▸ | CA12 | O43570 | 3/20 | 0.73 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.73 |
| ▸ | CA7 | P43166 | 2/20 | 0.73 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3117611 | 1.00 | PPARA (1.00) | PPARACA1CA2CA12CA14 | |
| SCHEMBL18644318 | 1.00 | PPARA (1.00) | PPARACA1CA2CA12CA14 | |
| SCHEMBL3119510 | 1.00 | PPARA (1.00) | PPARACA1CA2CA12CA14 | |
| SCHEMBL10892940 | 0.95 | PPARA (0.91) | PPARACA1CA2CA12CA14 | |
| SCHEMBL9285865 | 0.95 | PPARA (0.91) | PPARACA1CA2CA12CA14 | |
| SCHEMBL3792249 | 0.95 | PPARA (0.91) | PPARACA1CA2CA12CA14 | |
| SCHEMBL4563383 | 0.93 | PPARA (0.86) | PPARACA1CA2CA12CA14 | |
| SCHEMBL3803009 | 0.88 | PPARA (0.79) | PPARACA1CA2CA12CA14 | |
| SCHEMBL3114654 | 0.88 | PPARA (1.00) | PPARACA1CA2CA12CA14 | |
| SCHEMBL3119679 | 0.88 | PPARA (1.00) | PPARACA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984326-B1 | ACYCLIC SULFAMIDE DERIVATIVES | FUND IMABIS INST MEDITTERANEO PARA EL AVAN E DE LA BIOTECNOLOGIA Y LA INVESTIG SANITARIA (ES) | 2017-05-03 | — | — | EP | claimed |
| US-8188312-B2 | Acyclic sulfamide derivatives | FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) | 2012-05-29 | — | — | US | claimed |
| US-20100179224-A2 | Acyclic Sulfamide Derivatives | FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) | 2010-07-15 | — | — | US | claimed |
| US-20100048712-A2 | Acyclic Sulfamide Derivatives | FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) | 2010-02-25 | — | — | US | claimed |
| US-20090221710-A1 | Acyclic Sulfamide Derivatives | FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) | 2009-09-03 | — | — | US | claimed |
| EP-1984326-A1 | ACYCLIC SULFAMIDE DERIVATIVES | Fundacion Imabis. Inst. Meditteraneo para el Avan e de la Biotecnologia y la Investigacion Sanitaria (ES) | 2008-10-29 | — | — | EP | claimed |
| WO-2007085469-A1 | ACYCLIC SULFAMIDE DERIVATIVES | FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) | 2007-08-02 | — | — | WO | claimed |
| EP-1984326-B1 | ACYCLIC SULFAMIDE DERIVATIVES | FUND IMABIS INST MEDITTERANEO PARA EL AVAN E DE LA BIOTECNOLOGIA Y LA INVESTIG SANITARIA (ES) | 2017-05-03 | — | — | EP | disclosed |
| US-8188312-B2 | Acyclic sulfamide derivatives | FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) | 2012-05-29 | — | — | US | disclosed |
| US-20100179224-A2 | Acyclic Sulfamide Derivatives | FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) | 2010-07-15 | — | — | US | disclosed |
| US-20100048712-A2 | Acyclic Sulfamide Derivatives | FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) | 2010-02-25 | — | — | US | disclosed |
| US-20090221710-A1 | Acyclic Sulfamide Derivatives | FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) | 2009-09-03 | — | — | US | disclosed |
| EP-1984326-A1 | ACYCLIC SULFAMIDE DERIVATIVES | Fundacion Imabis. Inst. Meditteraneo para el Avan e de la Biotecnologia y la Investigacion Sanitaria (ES) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007085469-A1 | ACYCLIC SULFAMIDE DERIVATIVES | FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179224-A2 | Acyclic Sulfamide Derivatives | SULT2A1, STS, SUCNR1 | PPARA 346/4885CA1 1840/4885CA2 1092/4885 |
| US-20090221710-A1 | Acyclic Sulfamide Derivatives | STS, LIPE, FABP4 | PPARA 30/4885CA1 3726/4885CA2 2198/4885 |
| US-20100048712-A2 | Acyclic Sulfamide Derivatives | SULT2A1, STS, SUCNR1 | PPARA 346/4885CA1 1840/4885CA2 1092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.