⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921485 | 0.79 | — | — | |
| SCHEMBL11826734 | 0.75 | — | — | |
| SCHEMBL7551519 | 0.75 | — | — | |
| SCHEMBL5807433 | 0.75 | — | — | |
| SCHEMBL3206688 | 0.72 | ALDH1A1 (0.38) | — | |
| SCHEMBL22616854 | 0.72 | — | — | |
| SCHEMBL1760694 | 0.72 | — | — | |
| SCHEMBL6152885 | 0.72 | FDPS (0.30) | — | |
| SCHEMBL10870980 | 0.72 | FDPS (0.30) | — | |
| SCHEMBL11507122 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980297-A | Substituted aminopyridine compounds as EGFR inhibitors | 柳韩洋行 | 2024-05-03 | — | — | CN | claimed |
| US-5494750-A | HYDROSILATION WITH PLATINUM CATALYST AND RETARDING AGENT ENCAPSULATED BY SILICONE FOR EXCELLENT STORAGE STABILITY | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | claimed |
| US-20260042759-A1 | INHIBITOR CONTAINING BICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HANSOH BIOMEDICAL CO LTD (CN) | 2026-02-12 | — | — | US | disclosed |
| EP-4676591-A2 | SMALL MOLECULE FSH RECEPTOR MODULATORS | Ferring B.V. (NL) | 2026-01-14 | — | — | EP | disclosed |
| US-12502376-B2 | Pyrano[4,3-b]indole derivatives as alpha-1-antitrypsin modulators for treating alpha-1-antitrypsin deficiency (AATD) | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-12-23 | — | — | US | disclosed |
| US-12466823-B2 | Inhibitor containing bicyclic derivative, preparation method therefor and use thereof | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2025-11-11 | — | — | US | disclosed |
| US-20250257076-A1 | SUBSTITUTED PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AS cGAS INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-14 | — | — | US | disclosed |
| US-12331057-B2 | Modulators of alpha-1 antitrypsin | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-06-17 | — | — | US | disclosed |
| EP-3971187-B1 | INHIBITOR CONTAINING BICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HANSOH BIOMEDICAL CO LTD (CN) | 2025-05-07 | — | — | EP | disclosed |
| US-20240424113-A1 | CONJUGATES COMPRISING ANTIFUNGALS AND HEAT SHOCK PROTEIN 90 (HSP90) INHIBITORS AND METHODS OF USE THEREOF | BRIGHT ANGEL THERAPEUTICS INC. (CA) | 2024-12-26 | — | — | US | disclosed |
| US-20240336614-A1 | MODULATORS OF ALPHA-1 ANTITRYPSIN | VERTEX PHARMACEUTICALS INCORPORATED | 2024-10-10 | — | — | US | disclosed |
| US-5494750-A | HYDROSILATION WITH PLATINUM CATALYST AND RETARDING AGENT ENCAPSULATED BY SILICONE FOR EXCELLENT STORAGE STABILITY | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| US-5085685-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |
| US-4871868-A | FROM AN ORGANIC HALIDE OR AN ARYL SULFONATE AND AN ALKALI METAL ACETYLIDE, 1,3-DIALKYL-2-IMIDAZOLIDINONE PROMOTER | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| EP-0284237-A1 | Production of substituted acetylenic compounds | Takeda Chemical Industries, Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |
| US-4670186-A | Acid inhibitor composition | PETROLITE CORPORATION (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0007828-B1 | PROCESS FOR PREPARING ALKYL ESTERS OF DL-CIS CHRYSANTHEMIC ACID | ROUSSEL-UCLAF (FR) | 1981-11-04 | — | — | EP | disclosed |
| US-4233129-A | Process of preparation of alkyl esters of dl cis chrysanthemic acid | ROUSSEL UCLAF (FR) | 1980-11-11 | — | — | US | disclosed |
| EP-0007828-A1 | Process for preparing alkyl esters of dl-cis chrysanthemic acid | ROUSSEL-UCLAF (FR) | 1980-02-06 | — | — | EP | disclosed |
| US-3989601-A | TERTIARY ALCOHOLS, MONOCARBOXYLIC ACIDS AND ANHYDRIDES | THE DOW CHEMICAL COMPANY (US) | 1976-11-02 | — | — | US | disclosed |