SCHEMBL6152885

SCHEMBL6152885

C#CCC(C)(O)CCCC

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.30
GGPS1 O95749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10371008 1.00 FDPS (0.30) FDPSGGPS1
SCHEMBL10870980 1.00 FDPS (0.30) FDPSGGPS1
SCHEMBL5807433 0.86
SCHEMBL11572734 0.86
SCHEMBL11252355 0.80
SCHEMBL11055877 0.79 CES2 (0.37)
SCHEMBL11343846 0.78 CES1 (0.32)
SCHEMBL808879 0.77 ALDH1A1 (0.39) FDPSGGPS1
SCHEMBL13650261 0.76
SCHEMBL11644004 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62175434-A None JP disclosed
JP-2279645-A None JP disclosed
EP-0943607-B1 PROCESS FOR THE PREPARATION OF PROSTAGLANDINS DAIICHI FINE CHEM CO LTD (JP) 2005-01-26 EP disclosed
US-6313341-B1 Process for the preparation of prostaglandins FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 2001-11-06 US disclosed
EP-0943607-A1 PROCESS FOR THE PREPARATION OF PROSTAGLANDINS FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1999-09-22 EP disclosed
JP-H02279645-A NOVEL ALCOHOL AND ITS PRODUCTION SUMITOMO CHEM CO LTD 1990-11-15 JP disclosed
US-4922032-A Process for the preparation of optically active 2-methyl-1,2-hexanediols CENTRO DE INVESTIGACION Y DE ESTUDIOS AVANZADOS DEL INSTITUTO POLITECNICO NACIONAL (MX) 1990-05-01 US disclosed
US-4833157-A ANTIULCER AGENTS MILES INC. (US) 1989-05-23 US disclosed
US-4742080-A Therapeutic method for producing bronchodilation by administration of 15-deoxy-16-hydroxy prostaglandin esters MILES LABORATORIES, INC. (US) 1988-05-03 US disclosed
JP-S62175434-A PRODUCTION OF 4-METHYL-4-HYDROXY-1-OCTYNE COMPOUND TEIJIN LTD 1987-08-01 JP disclosed
US-4165331-A PROSTAGLANDINS/AND DERIVATIVES AMERICAN CYANAMID COMPANY (US) 1979-08-21 US disclosed
EP-0002590-A1 Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-06-27 EP disclosed
US-4154959-A 11-(2-Hydroxyethylthio)prostenoic acid E series derivatives AMERICAN CYANAMID COMPANY (US) 1979-05-15 US disclosed
US-4154954-A BRONCHODILATOR AGENTS; ANTIINFLAMMATORY AGENTS AMERICAN CYANAMID COMPANY (US) 1979-05-15 US disclosed
US-4132738-A BRONCHODILATORS, ANTISECRETORY AGENTS MILES LABORATORIES, INC. (US) 1979-01-02 US disclosed
US-4107441-A HYPOTENSIVE, ANTIULCER, BRONCHODILATORS, ANTIMICROBIAL, ANTICONVULSANTS AMERICAN CYANAMID COMPANY (US) 1978-08-15 US disclosed
US-4087621-A 7-{3-Hydroxy-2β-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-oxocyclopent-1α-yl}hept-5-cis-enoic acids and related compounds G. D. SEARLE & CO. (US) 1978-05-02 US disclosed
US-4085272-A BRONCHODILATORS, INFLAMMATORY MEDEATOR RELEASE INHIBITORS AMERICAN CYANAMID COMPANY (US) 1978-04-18 US disclosed
US-4060691-A 7-{3-Hydroxy-2-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-oxocyclopent-1-yl}heptanoic acids and esters G. D. SEARLE & CO. (US) 1977-11-29 US disclosed
US-3965143-A 16-Oxygenated prostanoic acid derivatives G. D. SEARLE & CO. (US) 1976-06-22 US disclosed