Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15043602 | 0.86 | CACNA1B (0.39) | KDM4EKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL913292 | 0.75 | SMN1; SMN2 (0.38) | KDM4EKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL157545 | 0.73 | PTGS1 (0.41) | ALDH1A1PSMB8MAPK1SMN1; SMN2MGLL | |
| SCHEMBL12309023 | 0.73 | CYP2D6 (0.33) | KMT2AMEN1GAAALDH1A1PSMB8 | |
| SCHEMBL30357859 | 0.72 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1PSMB8SMN1; SMN2 | |
| SCHEMBL43576 | 0.70 | PSMB8 (0.35) | KMT2APSMB8MAPK1SMN1; SMN2MGLL | |
| Acetonitrile SCHEMBL6034850 | 0.69 | HPGD (0.36) | ALDH1A1PSMB8MAPK1SMN1; SMN2MGLL | |
| SCHEMBL20022878 | 0.69 | HPGD (0.36) | KMT2AMEN1ALDH1A1PSMB8SMN1; SMN2 | |
| SCHEMBL31522720 | 0.68 | PSMB8 (0.34) | KMT2APSMB8SMN1; SMN2MGLLPSMB5 | |
| SCHEMBL19658319 | 0.68 | SMN1; SMN2 (0.36) | KDM4EKMT2AMEN1ALDH1A1PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025646-A1 | MALEIMIDE‑FURANYL COMPOUNDS THAT CAN BE USED IN A GENERAL METHOD FOR PREPARING MALEIMIDE‑OLIGONUCLEOTIDE DERIVATIVES | UNIVERSITAT DE BARCELONA (ES) | 2012-03-01 | — | — | WO | disclosed |