Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 7/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31212 | 0.86 | KDM4E (0.34) | ALDH1A1MAPK1KMT2AMEN1KDM4E | |
| SCHEMBL913292 | 0.74 | SMN1; SMN2 (0.38) | ALDH1A1HPGDHTTHSD17B10KMT2A | |
| SCHEMBL157545 | 0.72 | PTGS1 (0.41) | ALDH1A1MAPK1TP53HPGDHTT | |
| SCHEMBL12309023 | 0.72 | CYP2D6 (0.33) | ALDH1A1KMT2AMEN1PSMB8GAA | |
| SCHEMBL30357859 | 0.71 | ALDH1A1 (0.51) | ALDH1A1HPGDHTTRAB9AKMT2A | |
| SCHEMBL21441627 | 0.70 | CACNA1B (0.50) | CACNA1BAPBA1ALDH1A1MAPK1TP53 | |
| SCHEMBL15043597 | 0.70 | CACNA1B (0.50) | CACNA1BAPBA1ALDH1A1MAPK1TP53 | |
| SCHEMBL31722261 | 0.69 | PTGS1 (0.50) | CACNA1BAPBA1ALDH1A1MAPK1TP53 | |
| SCHEMBL43576 | 0.69 | PSMB8 (0.35) | MAPK1HPGDLMNAATMKMT2A | |
| Acetonitrile SCHEMBL6034850 | 0.69 | HPGD (0.36) | ALDH1A1MAPK1TP53HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816062-B2 | Maleimide-furanyl compounds that can be used in a general method for preparing maleimide-oligonucleotide derivatives | UNIVERSITAT DE BARCELONA (ES) | 2014-08-26 | — | — | US | disclosed |
| US-20130158248-A1 | MALEIMIDE-FURANYL COMPOUNDS THAT CAN BE USED IN A GENERAL METHOD FOR PREPARING MALEIMIDE-OLIGONUCLEOTIDE DERIVATIVES | UNIVERSITAT DE BARCELONA (ES) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158248-A1 | MALEIMIDE-FURANYL COMPOUNDS THAT CAN BE USED IN A GENERAL METHOD FOR PREPARING MALEIMIDE-OLIGONUCLEOTIDE DERIVATIVES | NSUN2, POLL, NT5C3B | CACNA1B 2908/4885APBA1 1172/4885ALDH1A1 4111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.