SCHEMBL312132

SCHEMBL312132

COc1c(C)cc(C(=O)O)cc1C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 7/20 0.55
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA12 O43570 2/20 0.52
CA4 P22748 2/20 0.52
CA6 P23280 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
CA3 P07451 1/20 0.52
PKM P14618 1/20 0.52
CA5A P35218 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
PTGS2 P35354 1/20 0.48
ALDH1A1 P00352 2/20 0.47
CNR2 P34972 1/20 0.47
TAS1R3 Q7RTX0 1/20 0.45
TAS1R1 Q7RTX1 1/20 0.45
HCAR1 Q9BXC0 1/20 0.43
KDM4E B2RXH2 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11851061 0.98 TPMT (0.53) TPMTCA1CA2CA12CA4
SCHEMBL21711825 0.88 TPMT (0.68) TPMTCA1CA2CA12CA4
SCHEMBL3355977 0.88 TPMT (0.68) TPMTCA1CA2CA12CA4
SCHEMBL27801015 0.88 TPMT (0.49) TPMTCA1CA2CA12CA4
SCHEMBL21880315 0.86 TPMT (0.69) TPMTCA1CA2CA12CA4
SCHEMBL11435411 0.84 TUBB4A (0.54) ALDH1A1TAS1R3TAS1R1
SCHEMBL7792403 0.83 TNFRSF1A (0.48) TPMTCA1CA2CA12CA4
SCHEMBL7824262 0.83 ALDH1A1 (0.43) TPMTCA1CA2CA12CA4
SCHEMBL2796551 0.82 LMNA (0.52) TPMTPKMCA5AALDH1A1TAS1R3
SCHEMBL7824257 0.82 TPMT (0.41) TPMTCA1CA2CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4559009-A2 PARTICLES Life Technologies AS (NO) 2025-05-28 EP claimed
CN-119698673-A Particles 生命技术股份公司 2025-03-25 CN claimed
CN-119465669-A Dyeing liquid for optical resin, dyed optical resin, and preparation method and application of dyed optical resin 拓烯科技(衢州)有限公司 2025-02-18 CN claimed
CN-119194880-A Dyeing assistant composition for optical resin dyeing, dyeing method of optical resin and dyed optical resin 拓烯科技(衢州)有限公司 2024-12-27 CN claimed
CN-118621601-A Dyeing liquid for optical resin and preparation method and application thereof 拓烯科技(衢州)有限公司 2024-09-10 CN claimed
WO-2024018084-A2 PARTICLES LIFE TECHNOLOGIES AS (NO) 2024-01-25 WO claimed
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-10-09 US disclosed
EP-4559009-A2 PARTICLES Life Technologies AS (NO) 2025-05-28 EP disclosed
EP-4536653-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME Eisai R&D Management Co., Ltd. (JP) 2025-04-16 EP disclosed
CN-119698673-A Particles 生命技术股份公司 2025-03-25 CN disclosed
CN-119465669-A Dyeing liquid for optical resin, dyed optical resin, and preparation method and application of dyed optical resin 拓烯科技(衢州)有限公司 2025-02-18 CN disclosed
CN-119194880-A Dyeing assistant composition for optical resin dyeing, dyeing method of optical resin and dyed optical resin 拓烯科技(衢州)有限公司 2024-12-27 CN disclosed
CN-118621601-A Dyeing liquid for optical resin and preparation method and application thereof 拓烯科技(衢州)有限公司 2024-09-10 CN disclosed
US-5563142-A INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE THE UPJOHN COMPANY (US) 1996-10-08 US disclosed
EP-0507861-B1 DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS UPJOHN CO (US) 1996-09-11 EP disclosed
WO-1996003387-A1 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-02-08 WO disclosed
US-5489593-A Anti-aids piperazines THE UPJOHN COMPANY (US) 1996-02-06 US disclosed
EP-0507861-A1 DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS. UPJOHN CO (US) 1992-10-14 EP disclosed
WO-1991009849-A1 DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS THE UPJOHN COMPANY (US) 1991-07-11 WO disclosed
US-4001426-A HAVING CORONARY VASODILATOR ACTIVITY SMITHKLINE CORPORATION (US) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME NEU1, NEU2, NEU4 TPMT 2508/4885CA1 95/4885CA2 1654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.