Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | RHEB | Q15382 | 6/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31215307 | 0.90 | RHEB (0.51) | SRD5A2KDM4EHPGDCYP2C9ALDH1A1 | |
| SCHEMBL31215274 | 0.89 | RHEB (0.50) | SRD5A2KDM4EHPGDCYP2C9ALDH1A1 | |
| SCHEMBL31215309 | 0.89 | SRD5A2 (0.49) | SRD5A2KDM4EHPGDCYP2C9ALDH1A1 | |
| SCHEMBL31215293 | 0.88 | THRA (0.48) | SRD5A2RHEBTHRATHRBGRIN1 | |
| SCHEMBL31215290 | 0.87 | THRA (0.56) | SRD5A2KDM4EHPGDCYP2C9ALDH1A1 | |
| SCHEMBL31215284 | 0.86 | RHEB (0.47) | SRD5A2RHEBTHRATHRBGRIN1 | |
| SCHEMBL31215288 | 0.86 | THRA (0.48) | SRD5A2KDM4EHPGDCYP2C9ALDH1A1 | |
| SCHEMBL31215295 | 0.86 | KDM4E (0.46) | SRD5A2KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL31215283 | 0.86 | THRA (0.49) | SRD5A2THRATHRBPDGFRA | |
| SCHEMBL31215292 | 0.85 | THRA (0.48) | SRD5A2KDM4EHPGDCYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118894802-A | Selective THR beta agonist compound and application thereof | 山东第一医科大学(山东省医学科学院) | 2024-11-05 | — | — | CN | disclosed |