Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31215311 | 0.89 | MRGPRX4 (0.47) | THRATHRBMRGPRX4SRD5A2S1PR1 | |
| SCHEMBL31215284 | 0.89 | RHEB (0.47) | THRATHRBMRGPRX4SRD5A2 | |
| SCHEMBL31215309 | 0.86 | SRD5A2 (0.49) | THRATHRBNR4A2MRGPRX4SRD5A2 | |
| SCHEMBL31215276 | 0.86 | SRD5A2 (0.58) | THRATHRBSRD5A2PDGFRA | |
| SCHEMBL31215302 | 0.82 | THRA (0.43) | THRATHRBMRGPRX4SRD5A2FFAR4 | |
| SCHEMBL31215305 | 0.81 | RHEB (0.48) | THRATHRBMRGPRX4SRD5A2MAOB | |
| SCHEMBL31215282 | 0.80 | MRGPRX4 (0.42) | THRATHRBMRGPRX4SRD5A2FFAR4 | |
| SCHEMBL31215307 | 0.79 | RHEB (0.51) | THRATHRBSRD5A2 | |
| SCHEMBL31215274 | 0.78 | RHEB (0.50) | THRATHRBMRGPRX4SRD5A2 | |
| SCHEMBL31215292 | 0.77 | THRA (0.48) | THRATHRBMRGPRX4SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118894802-A | Selective THR beta agonist compound and application thereof | 山东第一医科大学(山东省医学科学院) | 2024-11-05 | — | — | CN | disclosed |