Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RHEB | Q15382 | 7/20 | 0.41 |
| ▸ | IDO1 | P14902 | 5/20 | 0.39 |
| ▸ | TDO2 | P48775 | 5/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31215319 | 0.86 | THRA (0.48) | THRATHRBRHEBGRIN1TDP1 | |
| SCHEMBL31215308 | 0.82 | THRA (0.46) | THRATHRBRHEBIDO1TDO2 | |
| SCHEMBL31215309 | 0.81 | SRD5A2 (0.49) | THRATHRBRHEBIDO1TDO2 | |
| SCHEMBL31215293 | 0.80 | THRA (0.48) | THRATHRBRHEBGRIN1SRD5A2 | |
| SCHEMBL31215274 | 0.79 | RHEB (0.50) | THRATHRBRHEBIDO1TDO2 | |
| SCHEMBL31215292 | 0.78 | THRA (0.48) | THRATHRBRHEBIDO1TDO2 | |
| SCHEMBL31215276 | 0.78 | SRD5A2 (0.58) | THRATHRBRHEBIDO1TDO2 | |
| SCHEMBL31215305 | 0.78 | RHEB (0.48) | THRATHRBRHEBIDO1TDO2 | |
| SCHEMBL31215307 | 0.76 | RHEB (0.51) | THRATHRBRHEBGRIN1KDM4E | |
| SCHEMBL31215290 | 0.75 | THRA (0.56) | THRATHRBRHEBGRIN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118894802-A | Selective THR beta agonist compound and application thereof | 山东第一医科大学(山东省医学科学院) | 2024-11-05 | — | — | CN | disclosed |