Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 5/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31215284 | 0.90 | RHEB (0.47) | MRGPRX4THRATHRBGRIN1RHEB | |
| SCHEMBL31215283 | 0.89 | THRA (0.49) | MRGPRX4THRATHRBSRD5A2S1PR1 | |
| SCHEMBL31215292 | 0.83 | THRA (0.48) | MRGPRX4THRATHRBGRIN1RHEB | |
| SCHEMBL31215276 | 0.82 | SRD5A2 (0.58) | THRATHRBGRIN1RHEBSRD5A2 | |
| SCHEMBL31215307 | 0.81 | RHEB (0.51) | THRATHRBGRIN1RHEBSRD5A2 | |
| SCHEMBL31215305 | 0.80 | RHEB (0.48) | MRGPRX4THRATHRBGRIN1RHEB | |
| SCHEMBL31215274 | 0.80 | RHEB (0.50) | MRGPRX4THRATHRBGRIN1RHEB | |
| SCHEMBL31215288 | 0.79 | THRA (0.48) | MRGPRX4THRATHRBGRIN1RHEB | |
| SCHEMBL31215309 | 0.79 | SRD5A2 (0.49) | MRGPRX4THRATHRBGRIN1RHEB | |
| SCHEMBL31215302 | 0.79 | THRA (0.43) | MRGPRX4THRATHRBGRIN1RHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118894802-A | Selective THR beta agonist compound and application thereof | 山东第一医科大学(山东省医学科学院) | 2024-11-05 | — | — | CN | disclosed |