⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132292 | 0.97 | FDPS (0.36) | — | |
| Hydrochloric Acid SCHEMBL11682972 | 0.95 | FDPS (0.34) | — | |
| SCHEMBL18724534 | 0.94 | — | — | |
| SCHEMBL18724744 | 0.79 | MC4R (0.38) | — | |
| SCHEMBL36573 | 0.77 | MAPT (0.39) | — | |
| SCHEMBL10760912 | 0.77 | FDPS (0.40) | — | |
| SCHEMBL1819138 | 0.77 | CHRM2 (0.34) | — | |
| SCHEMBL18724677 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL29771945 | 0.75 | — | — | |
| SCHEMBL27737518 | 0.74 | SIGMAR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002464-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | SAPIENSBIO INC. (KR) | 2025-01-02 | — | — | US | claimed |
| EP-4421070-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Sapiensbio Inc. (KR) | 2024-08-28 | — | — | EP | claimed |
| CN-118119612-A | Novel compounds and pharmaceutical compositions comprising the same | 萨皮恩斯生物有限公司 | 2024-05-31 | — | — | CN | claimed |
| WO-2023068755-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 사피엔스바이오 | 2023-04-27 | — | — | WO | claimed |
| EP-1487806-B1 | 4-ANILINO QUINAZOLINE DERIVATIVES AS ANTIPROLIFERATIVE AGENTS | ASTRAZENECA AB (SE) | 2010-07-07 | — | — | EP | claimed |
| US-20250002464-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | SAPIENSBIO INC. (KR) | 2025-01-02 | — | — | US | disclosed |
| EP-4421070-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Sapiensbio Inc. (KR) | 2024-08-28 | — | — | EP | disclosed |
| CN-118119612-A | Novel compounds and pharmaceutical compositions comprising the same | 萨皮恩斯生物有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-102822171-B | As the benzo naphthyridines amine of autotaxin inhibitors | MERCK PATENT GMBH (DE) | 2015-09-02 | — | — | CN | disclosed |
| CN-102595893-B | Spirolactam derivatives and uses of same | LUNDBECK & CO AS H | 2014-12-31 | — | — | CN | disclosed |
| CN-101611005-B | Substituted acetophenones useful as PDE4 inhibitors | LEO PHARMA AS | 2013-11-06 | — | — | CN | disclosed |
| US-8399667-B2 | 4-anilino quinazoline derivatives as antiproliferative agents | ASTRAZENECA AB (GB) | 2013-03-19 | — | — | US | disclosed |
| US-5245052-A | PROCESS FOR PRODUCING 6-ACYL-7-DEACETYLFORSKOLIN DERIVATIVES | NIPPON KAYAKU CO. LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| CN-1016869-B | Process for preparing 6, 7-diacyl-7-deacetylforskolin derivatives | NIPPON KAYAKU KK (JP) | 1992-06-03 | — | — | CN | disclosed |
| CN-1060291-A | The novel method of preparation 6-acyl group-7-deacetylforskolin derivatives | HOECHST JAPAN (JP) | 1992-04-15 | — | — | CN | disclosed |
| EP-0469428-A1 | Novel process for producing 6-acyl-7-deacetylforskolin derivatives | HOECHST JAPAN LIMITED (JP) | 1992-02-05 | — | — | EP | disclosed |
| CN-1030583-A | Preparation 6,7-diacyl-7-takes off the novel method of acetyl forskrine derivant | NIPPON KAYAKU KK (JP) | 1989-01-25 | — | — | CN | disclosed |
| EP-0297496-A2 | Novel process for the preparation of 6,7-Diacyl-7-deacetylforskolin derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1989-01-04 | — | — | EP | disclosed |
| EP-0236140-A2 | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |
| US-4093812-A | MICROBIOCIDES, DISINFECTANTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) | 1978-06-06 | — | — | US | disclosed |