Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643733 | 0.96 | KCNH2 (0.59) | KCNH2SIGMAR1HTR2ACETPESR1 | |
| SCHEMBL31216299 | 0.92 | SIGMAR1 (0.50) | KCNH2SIGMAR1HTR2ACETPTP53 | |
| SCHEMBL24849454 | 0.92 | SIGMAR1 (0.50) | KCNH2SIGMAR1HTR2ACETPTP53 | |
| SCHEMBL15150830 | 0.88 | MEN1 (0.48) | KCNH2SIGMAR1HTR2AADRA2ASLC6A2 | |
| SCHEMBL1882499 | 0.85 | MAOA (0.58) | SIGMAR1HTR2ASLC6A3ALDH1A1HSD17B10 | |
| SCHEMBL8389964 | 0.84 | SIGMAR1 (0.48) | KCNH2SIGMAR1HTR2ACETPADRA2A | |
| SCHEMBL8678550 | 0.83 | KCNH2 (0.71) | KCNH2SIGMAR1HTR2ACETPESR1 | |
| SCHEMBL29401 | 0.83 | KCNH2 (0.71) | KCNH2SIGMAR1HTR2ACETPESR1 | |
| SCHEMBL4932286 | 0.83 | KCNH2 (0.71) | KCNH2SIGMAR1HTR2ACETPESR1 | |
| Benzene SCHEMBL8518570 | 0.83 | KCNH2 (0.71) | KCNH2SIGMAR1HTR2ACETPESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852230-A | Preparation method of polysubstituted hydrosilane compound | 中国科学院兰州化学物理研究所 | 2024-10-29 | — | — | CN | disclosed |