Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 2/20 | 0.42 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25111970 | 1.00 | GAA (0.44) | GAAHSD17B10SMN1; SMN2MAPTNPC1 | |
| SCHEMBL21683098 | 0.86 | HSD17B10 (0.44) | GAAHSD17B10SMN1; SMN2MAPTNPC1 | |
| SCHEMBL19627251 | 0.84 | RAB9A (0.42) | GAAHSD17B10SMN1; SMN2MAPTNPC1 | |
| SCHEMBL11591003 | 0.81 | HSD17B10 (0.68) | GAAHSD17B10SMN1; SMN2MAPTNPC1 | |
| SCHEMBL18863820 | 0.81 | HSD17B10 (0.41) | GAAHSD17B10ALDH1A1NQO2NSD1 | |
| SCHEMBL12109842 | 0.81 | ALDH1A1 (0.39) | GAAHSD17B10SMN1; SMN2MAPTNPC1 | |
| SCHEMBL21091519 | 0.81 | NSD1 (0.64) | GAAHSD17B10SMN1; SMN2MAPTNPC1 | |
| SCHEMBL10272977 | 0.79 | HSD17B10 (0.66) | GAAHSD17B10SMN1; SMN2MAPTNPC1 | |
| SCHEMBL31210403 | 0.78 | MAPT (0.50) | GAAHSD17B10SMN1; SMN2MAPTNPC1 | |
| SCHEMBL20049335 | 0.77 | GAA (0.41) | GAAHSD17B10SMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111065626-B | Compounds for the treatment of huntington's disease | PTC医疗公司 | 2024-09-27 | — | — | CN | disclosed |