Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21996926 | 0.84 | SMN1; SMN2 (0.49) | SIGMAR1TMEM97L3MBTL1NPSR1 | |
| SCHEMBL30872630 | 0.80 | FKBP1A (0.48) | SIGMAR1TMEM97FKBP1AL3MBTL1NPSR1 | |
| SCHEMBL27140255 | 0.79 | SMN1; SMN2 (0.52) | NPSR1KDM4E | |
| SCHEMBL7813620 | 0.78 | FKBP1A (0.53) | SIGMAR1TMEM97FKBP1ANPSR1PREP | |
| SCHEMBL34474623 | 0.78 | PREP (0.47) | SIGMAR1L3MBTL1NPSR1PREPHTR2C | |
| SCHEMBL30511005 | 0.78 | PREP (0.47) | SIGMAR1L3MBTL1NPSR1PREPHTR2C | |
| SCHEMBL30958002 | 0.78 | KLK7 (0.49) | SIGMAR1TMEM97FKBP1AL3MBTL1KDM4E | |
| SCHEMBL21998139 | 0.77 | L3MBTL1 (0.56) | SIGMAR1L3MBTL1HTR2CSLC6A4LMNA | |
| SCHEMBL11489453 | 0.77 | TMEM97 (0.53) | SIGMAR1TMEM97FKBP1AL3MBTL1NPSR1 | |
| SCHEMBL6651386 | 0.77 | SMN1; SMN2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013277-A | TYK2 degrading agent and application thereof | 凯麦拉医疗公司 | 2024-11-22 | — | — | CN | disclosed |