Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31165294 | 0.81 | P2RX4 (0.52) | TP53MAPTKMT2AP2RX4POLB | |
| SCHEMBL31219198 | 0.81 | LMNA (0.51) | MAPTKMT2AP2RX4TSHRMAPK1 | |
| SCHEMBL31218963 | 0.81 | PTGS2 (0.64) | MAPTKMT2AHTR6P2RX4TSHR | |
| SCHEMBL31219083 | 0.81 | KMT2A (0.53) | PTGER4MAPTKMT2AHTR6P2RX4 | |
| SCHEMBL15457942 | 0.79 | TP53 (0.51) | TP53PTGER4MAPTKMT2AP2RX4 | |
| SCHEMBL15081217 | 0.79 | PSMD14 (0.45) | TP53MAPTKMT2APOLBLMNA | |
| SCHEMBL15081186 | 0.78 | PTGES2 (0.46) | TP53MAPTKMT2ALMNAMEN1 | |
| SCHEMBL14225842 | 0.78 | TP53 (0.49) | TP53MAPTKMT2AP2RX4POLB | |
| SCHEMBL31219037 | 0.77 | KMT2A (0.50) | MAPTKMT2AHTR6P2RX4TSHR | |
| SCHEMBL31219075 | 0.77 | KMT2A (0.50) | MAPTKMT2AHTR6P2RX4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024199444-A1 | HETEROAROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海翊维康医药有限责任公司 | 2024-10-03 | — | — | WO | disclosed |