Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31221182 | 0.90 | HRH4 (0.36) | CYP2C19HRH4HTR3AKDRRAB9A | |
| SCHEMBL31221020 | 0.77 | MAOA (0.43) | KMT2ACYP2A6 | |
| SCHEMBL31221024 | 0.77 | MAOA (0.43) | KMT2ACYP2A6 | |
| SCHEMBL14496908 | 0.71 | MAOA (0.39) | CYP2C19CYP2C9HRH4KDRCYP1A2 | |
| SCHEMBL25949938 | 0.70 | CYP2C19 (0.46) | CYP2C19CYP2C9ALDH1A1CYP1A2MAPT | |
| SCHEMBL31221174 | 0.69 | HTR6 (0.46) | CYP2C19CYP2C9ALDH1A1CYP1A2KDM4E | |
| SCHEMBL17090678 | 0.68 | MAOA (0.45) | HRH4HTR3AALDH1A1MAPTKDM4E | |
| SCHEMBL10272301 | 0.68 | MAPT (0.49) | CYP2C19CYP2C9ALDH1A1MAPTKDM4E | |
| SCHEMBL31221026 | 0.67 | L3MBTL1 (0.48) | CYP2C19CYP2C9ALDH1A1CYP1A2KDM4E | |
| SCHEMBL8353507 | 0.65 | KDM4E (0.49) | CYP2C19CYP2C9HRH4ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192175-A | Compound, pharmaceutical composition and application thereof | 北京康辰药业股份有限公司 | 2024-12-27 | — | — | CN | claimed |