Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.41 |
| ▸ | LPL | P06858 | 5/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483144 | 1.00 | CASP1 (0.45) | CASP1CASP7HSD17B10HSD17B1LPL | |
| SCHEMBL29984001 | 0.91 | MAOB (0.47) | HSD17B1LPLLIPGGRM5MAOA | |
| SCHEMBL27080470 | 0.91 | MAOB (0.47) | HSD17B1LPLLIPGGRM5MAOA | |
| SCHEMBL204451 | 0.89 | LPL (0.46) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL1226405 | 0.88 | PBRM1 (0.45) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL24411917 | 0.80 | LPL (0.39) | HSD17B1LPLLIPGROCK1MAOA | |
| SCHEMBL13070935 | 0.80 | LPL (0.39) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL29502333 | 0.80 | LPL (0.47) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL16639375 | 0.80 | LPL (0.47) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL1636716 | 0.80 | PARP10 (0.54) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676476-A1 | INHIBITORS OF TDP-43 AND TAU AGGREGATION | Aquinnah Pharmaceuticals, Inc. (US) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024187126-A1 | INHIBITORS OF TDP-43 AND TAU AGGREGATION | AQUINNAH PHARMACEUTICALS, INC. (US) | 2024-09-12 | — | — | WO | disclosed |