Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 13/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204451 | 0.91 | LPL (0.46) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL24411917 | 0.82 | LPL (0.39) | LPLLIPGROCK1ESR2F11 | |
| SCHEMBL202622 | 0.80 | LIPG (0.46) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL30860136 | 0.80 | LIPG (0.46) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL31222883 | 0.80 | CASP1 (0.45) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL483144 | 0.80 | CASP1 (0.45) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL15429671 | 0.79 | LIPG (0.49) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL16639375 | 0.79 | LPL (0.47) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL29502333 | 0.79 | LPL (0.47) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL17481114 | 0.78 | BACE1 (0.34) | LPLLIPGBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |