Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850407 | 0.85 | HPGD (0.46) | HPGDMEN1KMT2ANPC1TRPM8 | |
| SCHEMBL28689612 | 0.78 | CXCR1 (0.30) | GAA | |
| SCHEMBL28995164 | 0.78 | TRPM8 (0.50) | HPGDMEN1KMT2ANPC1TRPM8 | |
| SCHEMBL28995158 | 0.75 | TSPO (0.42) | HPGDKMT2ANPC1TRPM8ALDH1A1 | |
| SCHEMBL28995154 | 0.75 | TRPM8 (0.47) | HPGDMEN1KMT2ANPC1TRPM8 | |
| SCHEMBL28995157 | 0.74 | TSPO (0.47) | HPGDMEN1KMT2ANPC1TRPM8 | |
| SCHEMBL28995155 | 0.74 | TSPO (0.47) | HPGDMEN1KMT2ANPC1TRPM8 | |
| SCHEMBL28948520 | 0.74 | TRPM8 (0.44) | MEN1KMT2ANPC1TRPM8ALDH1A1 | |
| SCHEMBL28995170 | 0.73 | TSPO (0.40) | HPGDMEN1KMT2ATRPM8ALDH1A1 | |
| SCHEMBL28995151 | 0.73 | NR1H4 (0.43) | HPGDMEN1KMT2ATRPM8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118908891-A | Preparation method of 4-amino-2-quinolinone compound | 浙江广厦建设职业技术大学 | 2024-11-08 | — | — | CN | disclosed |