SCHEMBL534596

SCHEMBL534596

COc1ccc(-c2cc(=O)c3ccc(O)cc3o2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 1.00
TP53 P04637 6/20 1.00
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
CYP2C9 P11712 4/20 1.00
CYP2C19 P33261 4/20 1.00
TNKS O95271 3/20 1.00
TNKS2 Q9H2K2 1/20 1.00
MAPT P10636 6/20 0.87
ALDH1A1 P00352 6/20 0.87
KDM4E B2RXH2 5/20 0.87
HPGD P15428 5/20 0.87
HSD17B10 Q99714 4/20 0.87
CYP2D6 P10635 3/20 0.87
MAOB P27338 8/20 0.81
NPC1 O15118 4/20 0.80
RAB9A P51151 4/20 0.80
CSNK2A2 P19784 2/20 0.80
CSNK2B P67870 2/20 0.80
CSNK2A1 P68400 2/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30120666 1.00 CYP3A4 (1.00) CYP3A4TP53MEN1KMT2ACYP2C9
SCHEMBL30266579 0.93 CYP3A4 (1.00) CYP3A4TP53MEN1KMT2ACYP2C9
SCHEMBL312254 0.93 CYP3A4 (1.00) CYP3A4TP53MEN1KMT2ACYP2C9
4,7-Dimethoxyflavone SCHEMBL3470601 0.90 MAOB (1.00) CYP3A4TP53MEN1KMT2ACYP2C9
SCHEMBL31675989 0.89 MAPT (1.00) CYP3A4TP53MEN1KMT2ACYP2C9
SCHEMBL490928 0.89 MAPT (1.00) CYP3A4TP53MEN1KMT2ACYP2C9
SCHEMBL4404220 0.89 CYP3A4 (0.80) CYP3A4TP53MEN1KMT2ACYP2C9
SCHEMBL9663461 0.87 CSNK2A2 (0.87) CYP3A4TP53MEN1KMT2ACYP2C9
SCHEMBL31167385 0.87 CYP3A4 (1.00) CYP3A4TP53MEN1KMT2ACYP2C9
SCHEMBL157723 0.87 CYP3A4 (1.00) CYP3A4TP53MEN1KMT2ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698662-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2026-02-25 EP claimed
EP-2603098-B1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER FIRMENICH INCORPORATED (US) 2025-08-06 EP claimed
US-20250161459-A1 TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF ADARX PHARMACEUTICALS, INC. (US) 2025-05-22 US claimed
WO-2024220449-A9 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2025-04-03 WO claimed
WO-2025038960-A1 OLIGONUCLEOTIDES CONTAINING A LIGAND AT AN INTERNAL POSITION ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 WO claimed
WO-2024220449-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES ASKLEPIOS BIOPHARMACEUTICAL, INC. (US) 2024-10-24 WO claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
US-20110223256-A1 Method For Stabilizing Flavonoid Aqueous Dispersion STOKELY-VAN CAMP, INC. (US) 2011-09-15 US claimed
WO-2011112386-A1 METHOD FOR STABILIZING WATER INSOLUBLE BIOACTIVE COMPOUND AQUEOUS DISPERSIONS STOKELY-VAN CAMP, INC. (US) 2011-09-15 WO claimed
US-7767238-B2 Beverage composition and method of preventing degradation of vitamins in beverages PEPSICO, INC. (US) 2010-08-03 US claimed
WO-2010038153-A1 USE OF SOX TRANSCRIPTION FACTOR ACTI\\ATORS FOR STIMULATING CHONDROGENESIS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2010-04-08 WO claimed
CN-101069563-A Beverage composition and method for preventing degradation of vitamins in beverages PEPSICO INC (US) 2007-11-14 CN claimed
US-20070110851-A1 Beverage composition and method of preventing degradation of vitamins in beverages PEPSICO, INC. 2007-05-17 US claimed
EP-1782701-A1 Beverage composition and method of preventing degradation of vitamins in beverages PepsiCo, Inc. (US) 2007-05-09 EP claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
US-20040091589-A1 Prevention of synthetic color fading in beverages using botanically derived color stabilizers PEPSICO, INC. 2004-05-13 US claimed
EP-0124393-A1 Hair dyeing composition and process ALBAN MULLER INTERNATIONAL, S.A.R.L. (FR) 1984-11-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB CYP3A4 3571/4885TP53 297/4885MEN1 1711/4885
US-20250161459-A1 TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF NTRK2, NTRK1, BDNF CYP3A4 4808/4885TP53 2232/4885MEN1 4051/4885
US-20110223256-A1 Method For Stabilizing Flavonoid Aqueous Dispersion MLN, NSF, CEL CYP3A4 2694/4885TP53 868/4885MEN1 1705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.