SCHEMBL31228195

SCHEMBL31228195

CC(C)C(=O)OC[C@@]1(F)O[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ PRMT5 O14744 17/20 0.48
▸ WDR77 Q9BQA1 13/20 0.48
▸ ADK P55263 1/20 0.48
▸ DNMT1 P26358 1/20 0.45
▸ DNMT3B Q9UBC3 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31228122 0.92 PRMT5 (0.46) PRMT5WDR77ADKDNMT1DNMT3B
SCHEMBL31228249 0.85 PRMT5 (0.44) PRMT5WDR77ADKDNMT1DNMT3B
SCHEMBL31228198 0.82 ADK (0.57) PRMT5WDR77ADK
SCHEMBL31228119 0.79 P2RY1 (0.46) PRMT5WDR77ADK
SCHEMBL31725331 0.77 AHCY (0.53) PRMT5WDR77
SCHEMBL23622227 0.74 SLC28A1 (0.44) —
SCHEMBL21333519 0.74 SLC28A1 (0.44) —
SCHEMBL19401321 0.72 FAP (0.38) PRMT5WDR77ADKDNMT1DNMT3B
SCHEMBL31228134 0.72 ADK (0.55) PRMT5WDR77ADK
SCHEMBL31228185 0.71 PRMT5 (0.51) PRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 — — EP claimed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 — — WO claimed
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 — — EP disclosed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 — — WO disclosed
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