Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228568 | 0.75 | MTNR1A (0.30) | MTNR1AMTNR1B | |
| SCHEMBL23295457 | 0.72 | GPR84 (0.59) | MTNR1AMTNR1BGPR84 | |
| SCHEMBL8261743 | 0.70 | GPR84 (0.59) | GPR84 | |
| SCHEMBL1050738 | 0.69 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| SCHEMBL21060410 | 0.65 | FFAR1 (0.33) | GPR84 | |
| SCHEMBL24956777 | 0.65 | PSMD14 (0.41) | GPR84 | |
| SCHEMBL31405763 | 0.64 | MAPK1 (0.50) | MTNR1AMTNR1B | |
| SCHEMBL22070423 | 0.64 | MAPK1 (0.50) | MTNR1AMTNR1B | |
| SCHEMBL24214818 | 0.64 | MTNR1A (0.30) | MTNR1AMTNR1B | |
| SCHEMBL24688677 | 0.64 | SLC6A4 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688789-A1 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024211663-A9 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2025-01-30 | — | — | WO | disclosed |
| WO-2024211663-A1 | CONDENSED MACROCYCLIC COMPOUNDS AS RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2024-10-10 | — | — | WO | disclosed |