Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228472 | 0.86 | HSD17B10 (0.33) | HSD17B10 | |
| SCHEMBL31228461 | 0.86 | ALDH1A1 (0.30) | — | |
| SCHEMBL31228481 | 0.84 | HSD17B10 (0.38) | HSD17B10 | |
| SCHEMBL31228327 | 0.84 | — | — | |
| SCHEMBL31228285 | 0.77 | KLK7 (0.37) | — | |
| SCHEMBL31228414 | 0.72 | KMT2A (0.32) | — | |
| SCHEMBL31228409 | 0.69 | — | — | |
| SCHEMBL31228575 | 0.69 | MEN1 (0.33) | — | |
| SCHEMBL31228368 | 0.68 | MAPT (0.40) | — | |
| SCHEMBL31228346 | 0.66 | HSD17B10 (0.34) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688789-A1 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024211663-A9 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2025-01-30 | — | — | WO | disclosed |
| WO-2024211663-A1 | CONDENSED MACROCYCLIC COMPOUNDS AS RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2024-10-10 | — | — | WO | disclosed |