Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228414 | 0.87 | KMT2A (0.32) | KMT2A | |
| SCHEMBL31228327 | 0.87 | — | — | |
| SCHEMBL31228310 | 0.86 | HSD17B10 (0.30) | — | |
| SCHEMBL31228285 | 0.84 | KLK7 (0.37) | ALDH1A1KMT2A | |
| SCHEMBL31228368 | 0.81 | MAPT (0.40) | ALDH1A1KMT2A | |
| SCHEMBL31228189 | 0.78 | MMP3 (0.31) | KMT2A | |
| SCHEMBL31228362 | 0.78 | MMP3 (0.31) | KMT2A | |
| SCHEMBL31228509 | 0.78 | MMP3 (0.31) | KMT2A | |
| SCHEMBL31228393 | 0.76 | KLK7 (0.44) | ALDH1A1KMT2A | |
| SCHEMBL31228607 | 0.72 | ATM (0.31) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688789-A1 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024211663-A9 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2025-01-30 | — | — | WO | disclosed |
| WO-2024211663-A1 | CONDENSED MACROCYCLIC COMPOUNDS AS RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2024-10-10 | — | — | WO | disclosed |