Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 7/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31306238 | 1.00 | PPARA (0.49) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL955905 | 0.93 | ALDH1A1 (0.48) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL28821322 | 0.93 | ALDH1A1 (0.48) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL955903 | 0.93 | ALDH1A1 (0.48) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL20562065 | 0.92 | ALDH1A1 (0.50) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL20562067 | 0.92 | ALDH1A1 (0.50) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL31526993 | 0.91 | KLK5 (0.46) | PPARAPPARGACEPPARDCTSK | |
| SCHEMBL13643256 | 0.88 | CTSK (0.44) | PPARAPPARGACEPPARDCTSK | |
| SCHEMBL20974785 | 0.88 | PPARA (0.57) | PPARAPPARGACEPPARDIDO1 | |
| SCHEMBL15448116 | 0.88 | PPARA (0.57) | PPARAPPARGACEPPARDIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688789-A1 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025076523-A1 | RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |
| WO-2024211663-A9 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2025-01-30 | — | — | WO | disclosed |
| WO-2024211663-A1 | CONDENSED MACROCYCLIC COMPOUNDS AS RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2024-10-10 | — | — | WO | disclosed |