Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31306238 | 0.88 | PPARA (0.49) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL31228403 | 0.88 | PPARA (0.49) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL28408779 | 0.86 | ATM (0.43) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL19300689 | 0.86 | ATM (0.43) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL31526993 | 0.86 | KLK5 (0.46) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL30096601 | 0.86 | ATM (0.45) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL28523692 | 0.86 | ATM (0.45) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL21808744 | 0.85 | CTSK (0.48) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL21808745 | 0.85 | CTSK (0.48) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL2617388 | 0.85 | ATM (0.44) | CTSKCTSSCTSLCTSBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283287-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283287-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | KIF5B, KIF2C, PLK1 | CTSK 1842/4885CTSS 1766/4885CTSL 3872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.