Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31229571 | 0.82 | MEN1 (0.41) | LMNAMEN1KMT2ASMN1; SMN2JAK2 | |
| SCHEMBL31229553 | 0.81 | MEN1 (0.40) | LMNAMEN1KMT2ASMN1; SMN2JAK2 | |
| SCHEMBL31229507 | 0.81 | LMNA (0.40) | LMNAMEN1KMT2ASMN1; SMN2JAK2 | |
| SCHEMBL31229637 | 0.80 | LMNA (0.40) | LMNAMEN1KMT2ASMN1; SMN2JAK2 | |
| SCHEMBL31229581 | 0.79 | LMNA (0.49) | LMNAMEN1KMT2ASMN1; SMN2JAK2 | |
| SCHEMBL25148693 | 0.78 | MEN1 (0.42) | LMNAMEN1KMT2ASMN1; SMN2JAK2 | |
| SCHEMBL31229569 | 0.78 | JAK2 (0.37) | LMNAMEN1KMT2ASMN1; SMN2JAK2 | |
| SCHEMBL25148721 | 0.77 | LMNA (0.47) | LMNAMEN1KMT2ASMN1; SMN2JAK2 | |
| SCHEMBL25148716 | 0.77 | LMNA (0.47) | LMNAMEN1KMT2ASMN1; SMN2JAK2 | |
| SCHEMBL25149422 | 0.77 | LMNA (0.47) | LMNAMEN1KMT2ASMN1; SMN2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024222866-A1 | CYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2024-10-31 | — | — | WO | disclosed |