Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31229581 | 0.81 | LMNA (0.49) | JAK2TP53SMN1; SMN2LMNAMEN1 | |
| SCHEMBL31229541 | 0.78 | LMNA (0.40) | JAK2TP53SMN1; SMN2LMNAMEN1 | |
| SCHEMBL31229566 | 0.78 | LMNA (0.39) | JAK2TP53SMN1; SMN2LMNAMEN1 | |
| SCHEMBL25148723 | 0.78 | LMNA (0.44) | JAK2TP53SMN1; SMN2LMNAMEN1 | |
| SCHEMBL31229571 | 0.78 | MEN1 (0.41) | JAK2TP53SMN1; SMN2LMNAMEN1 | |
| SCHEMBL31229507 | 0.77 | LMNA (0.40) | JAK2TP53SMN1; SMN2LMNAMEN1 | |
| SCHEMBL31229553 | 0.77 | MEN1 (0.40) | JAK2TP53SMN1; SMN2LMNAMEN1 | |
| SCHEMBL31229812 | 0.77 | KDM4E (0.43) | HSD17B1HSD17B2 | |
| SCHEMBL31229637 | 0.76 | LMNA (0.40) | JAK2TP53SMN1; SMN2LMNAMEN1 | |
| SCHEMBL31229761 | 0.74 | ALDH1A1 (0.45) | JAK2SMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024222866-A1 | CYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2024-10-31 | — | — | WO | disclosed |