Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3120409 | 0.93 | LMNA (0.44) | NPC1LMNATSHRALOX15MAPK1 | |
| SCHEMBL3130536 | 0.85 | PDK2 (0.42) | NPC1LMNATSHRALOX15MAPK1 | |
| SCHEMBL8749753 | 0.84 | RAB9A (0.54) | NPC1TSHRRAB9AALDH1A1TSPO | |
| SCHEMBL5144078 | 0.82 | CYP1A2 (0.40) | NPC1LMNATSHRALOX15MAPK1 | |
| SCHEMBL17048204 | 0.81 | CYP4F2 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL3129660 | 0.80 | ALDH1A1 (0.36) | NPC1LMNATSHRALOX15MAPK1 | |
| SCHEMBL16390799 | 0.79 | PPARA (0.44) | LMNATSHRMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3123146 | 0.78 | ALDH1A1 (0.36) | NPC1LMNATSHRALOX15MAPK1 | |
| SCHEMBL3127319 | 0.78 | PDK2 (0.41) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16390865 | 0.78 | MAPT (0.44) | LMNATSHRHSD17B10SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |