Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 8/20 | 0.64 |
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | P4HB | P07237 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25195089 | 1.00 | KEAP1 (0.64) | KEAP1NFE2L2NPC1RAB9AMAPT | |
| SCHEMBL25198566 | 0.90 | KEAP1 (0.67) | KEAP1NFE2L2NPC1RAB9AMAPT | |
| SCHEMBL30383525 | 0.90 | KEAP1 (0.67) | KEAP1NFE2L2NPC1RAB9AMAPT | |
| SCHEMBL25219919 | 0.87 | KEAP1 (0.64) | KEAP1NFE2L2RAB9AMAPTHPGD | |
| SCHEMBL25189351 | 0.83 | KEAP1 (0.67) | KEAP1NFE2L2NPC1RAB9AMAPT | |
| SCHEMBL31233321 | 0.82 | MEN1 (0.64) | NPC1RAB9AMAPTP4HBPOLB | |
| SCHEMBL25195879 | 0.82 | MEN1 (0.64) | NPC1RAB9AMAPTP4HBPOLB | |
| SCHEMBL25192270 | 0.82 | CXCL12 (0.65) | KEAP1NFE2L2MAPTLMNA | |
| SCHEMBL25196048 | 0.82 | KEAP1 (0.56) | KEAP1NFE2L2MAPTALDH1A1LMNA | |
| SCHEMBL30382772 | 0.82 | KEAP1 (0.56) | KEAP1NFE2L2MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |