SCHEMBL31236768

SCHEMBL31236768

CCCCCCCCc1ccc2c3ccccc3c3ccccc3c2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORA P35398 1/20 0.58
RORC P51449 1/20 0.58
RORB Q92753 1/20 0.58
GPR3 P46089 1/20 0.53
SLC6A2 P23975 3/20 0.50
SLC6A4 P31645 3/20 0.50
HTR2A P28223 3/20 0.50
ESR1 P03372 2/20 0.50
ADRA2A P08913 2/20 0.50
ADORA3 P0DMS8 2/20 0.50
TACR2 P21452 2/20 0.50
SLC6A3 Q01959 2/20 0.50
HTR2C P28335 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
SHBG P04278 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
HSPD1 P10809 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9165312 1.00 RORA (0.58) RORARORCRORBGPR3SLC6A2
SCHEMBL20274701 0.92 RORA (0.50) RORARORCRORBGPR3CTSV
SCHEMBL28499912 0.88 CYP1A2 (0.55) RORARORCRORBGPR3SLC6A2
SCHEMBL18828889 0.85 GPR3 (0.48) RORARORCRORBGPR3HTR2A
SCHEMBL28421029 0.85 PTGS2 (0.52) RORARORCRORBSLC6A2SLC6A4
SCHEMBL1774311 0.85 RORA (0.49) RORARORCRORBGPR3SLC6A2
SCHEMBL7611678 0.83 KAT8 (0.49) RORARORCRORBSLC6A2SLC6A4
SCHEMBL7607203 0.83 KAT8 (0.49) RORARORCRORBSLC6A2SLC6A4
SCHEMBL27955065 0.83 PTGS2 (0.48) RORARORCRORBGPR3SLC6A2
SCHEMBL17994280 0.83 RORA (0.45) RORARORCRORBGPR3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12408914-B2 Systems and methods for customizing mechanical strength in stimuli-responsive bioabsorbable materials CILAG GMBH INTERNATIONAL (CH) 2025-09-09 US disclosed
EP-4543502-A1 SYSTEMS AND METHODS FOR CUSTOMIZING MECHANICAL STRENGTH IN STIMULI-RESPONSIVE BIOABSORBABLE MATERIALS Cilag GmbH International (CH) 2025-04-30 EP disclosed
US-20240423617-A1 SYSTEMS AND METHODS FOR CUSTOMIZING MECHANICAL STRENGTH IN STIMULI-RESPONSIVE BIOABSORBABLE MATERIALS CILAG GMBH INTERNATIONAL (CH) 2024-12-26 US disclosed
US-20240423620-A1 COMPRESSIBLE SURGICAL ADJUNCTS, CARTRIDGES, AND CARTRIDGE ASSEMBLIES AND METHODS OF MAKING SURGICAL ADJUNCTS CILAG GMBH INTERNATIONAL (CH) 2024-12-26 US disclosed
WO-2024261659-A1 SYSTEMS AND METHODS FOR CUSTOMIZING MECHANICAL STRENGTH IN STIMULI-RESPONSIVE BIOABSORBABLE MATERIALS CILAG GMBH INTERNATIONAL (CH) 2024-12-26 WO disclosed