Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.78 |
| ▸ | HPGD | P15428 | 11/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27823975 | 0.90 | KDM4E (0.92) | KDM4EALDH1A1HPGDCYP3A4HSD17B10 | |
| Dihydrosamidin SCHEMBL12062121 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1HPGDCYP3A4HSD17B10 | |
| Suksdorfin SCHEMBL15532093 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL31127004 | 0.83 | KDM4E (0.83) | KDM4EALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL29650634 | 0.82 | KDM4E (0.84) | KDM4EALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL29912933 | 0.82 | KDM4E (0.84) | KDM4EALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL14523893 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL29624043 | 0.77 | L3MBTL1 (1.00) | KDM4EALDH1A1HPGDCYP3A4HSD17B10 | |
| SCHEMBL4743847 | 0.77 | L3MBTL1 (1.00) | KDM4EALDH1A1HPGDCYP3A4HSD17B10 | |
| Seravshanin SCHEMBL30565432 | 0.74 | KDM4E (0.76) | KDM4EALDH1A1HPGDCYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |