Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 16/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 1.00 |
| ▸ | HPGD | P15428 | 12/20 | 1.00 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 0.80 |
| ▸ | HTT | P42858 | 3/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 3/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.80 |
| ▸ | RECQL | P46063 | 1/20 | 0.80 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.80 |
| ▸ | POLB | P06746 | 2/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380751 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1HPGDRCE1MAPT | |
| SCHEMBL29377909 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1HPGDRCE1MAPT | |
| SCHEMBL31682979 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1HPGDRCE1MAPT | |
| SCHEMBL29912890 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1HPGDRCE1MAPT | |
| SCHEMBL13363920 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1HPGDRCE1MAPT | |
| SCHEMBL29785360 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1HPGDRCE1MAPT | |
| SCHEMBL27783632 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1HPGDRCE1MAPT | |
| SCHEMBL4759420 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1HPGDRCE1MAPT | |
| SCHEMBL30517506 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1HPGDRCE1MAPT | |
| SCHEMBL30350458 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1HPGDRCE1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070092551-A1 | Therapeutic agent | FABP4, GPR119, IAPP | KDM4E 3790/4885ALDH1A1 951/4885HPGD 1524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.