Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.64 |
| ▸ | HPGD | P15428 | 10/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29624043 | 1.00 | L3MBTL1 (1.00) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL19419823 | 0.87 | L3MBTL1 (0.77) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL13799158 | 0.79 | L3MBTL1 (0.66) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL14523893 | 0.78 | KDM4E (1.00) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL31237484 | 0.77 | KDM4E (0.78) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL30565430 | 0.76 | TDP1 (0.64) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| (+)-Lomatin SCHEMBL29707947 | 0.75 | KDM4E (1.00) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| Lomatin SCHEMBL6273711 | 0.75 | KDM4E (1.00) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL4742405 | 0.72 | KDM4E (0.82) | L3MBTL1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL31598298 | 0.72 | KDM4E (0.82) | L3MBTL1TDP1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912556-B | Benzopyrone skeleton derivative and preparation method and application thereof | 复旦大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-109111419-B | 7, 8-coumarin derivative containing substituent, preparation method and application thereof | 复旦大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-112358457-B | Method for synthesizing chiral endocyclic lactone | 武汉大学 | 2022-07-05 | — | — | CN | disclosed |
| WO-2008100977-A2 | CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS | N.V. ORGANON (NL) | 2008-08-21 | — | — | WO | disclosed |
| CN-1636997-A | Substituted tricyclocoumarin compound and its prepn and anti-HIV application | INST OF TOXICANT PHARMACOLOGY (CN) | 2005-07-13 | — | — | CN | disclosed |
| US-20040162337-A1 | Lactone-type acidic compounds | CITY UNIVERSITY OF HONG KONG (HK) | 2004-08-19 | — | — | US | disclosed |
| EP-0810861-B1 | SUKSDORFIN ANALOGS, COMPOSITIONS THEREOF, AND METHODS FOR MAKING AND USING THEREOF | UNIV NORTH CAROLINA (US) | 2002-06-05 | — | — | EP | disclosed |
| US-6319929-B1 | VIRAL DISEASES AND HIV TREATMENT | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2001-11-20 | — | — | US | disclosed |
| US-5847165-A | Suksdorfin analogs, compositions thereof, and methods for making and using thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0810861-A4 | SUKSDORFIN ANALOGS, COMPOSITIONS THEREOF, AND METHODS FOR MAKING AND USING THEREOF | UNIV NORTH CAROLINA (US) | 1998-07-08 | — | — | EP | disclosed |
| US-5726204-A | RETROVIRUS INHIBITORS | BIOTECH RESEARCH LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0810861-A1 | SUKSDORFIN ANALOGS, COMPOSITIONS THEREOF, AND METHODS FOR MAKING AND USING THEREOF | The University of North Carolina at Chapel Hill (US) | 1997-12-10 | — | — | EP | disclosed |
| US-5637589-A | VIRICIDES; THERAPY FOR RETROVIRUS OR AIDS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1997-06-10 | — | — | US | disclosed |
| WO-1996025930-A1 | SUKSDORFIN ANALOGS, COMPOSITIONS THEREOF, AND METHODS FOR MAKING AND USING THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-08-29 | — | — | WO | disclosed |
| WO-1995029920-A1 | KHELLACTONE DERIVATIVES AND RELATED COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AND IMMUNOSTIMULATING AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1995-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162337-A1 | Lactone-type acidic compounds | ACSL1, ELOVL1, FASN | L3MBTL1 1435/4885TDP1 4639/4885KDM4E 4576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.