SCHEMBL31238543

SCHEMBL31238543

CC(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)O)C(C)C)C(C)C

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FURIN P09958 5/20 0.56
PCSK6 P29122 1/20 0.56
ALDH1A1 P00352 1/20 0.50
SIRT6 Q8N6T7 1/20 0.43
SIRT1 Q96EB6 1/20 0.43
PRSS1 P07477 1/20 0.42
CPB2 Q96IY4 4/20 0.42
GNPAT O15228 1/20 0.41
F2 P00734 1/20 0.41
F10 P00742 1/20 0.41
HPN P05981 1/20 0.41
HGFAC Q04756 1/20 0.41
ST14 Q9Y5Y6 1/20 0.41
CPA1 P15085 1/20 0.41
CPA2 P48052 1/20 0.41
CPA4 Q9UI42 1/20 0.41
NMT2 O60551 1/20 0.41
NMT1 P30419 1/20 0.41
FOLH1 Q04609 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30608459 0.90 FURIN (0.50) FURINPCSK6SIRT6SIRT1CPB2
SCHEMBL10381547 0.89 FURIN (0.48) FURINPCSK6CPB2
SCHEMBL10381550 0.89 FURIN (0.48) FURINPCSK6CPB2
SCHEMBL30374879 0.88 FOLH1 (0.50) FURINPCSK6ALDH1A1SIRT6SIRT1
SCHEMBL29520932 0.85 BACE1 (0.53) FURINPCSK6FOLH1
SCHEMBL29531524 0.85 NTSR2 (0.45) FURINPCSK6ALDH1A1CPB2
SCHEMBL29384387 0.85 NTSR2 (0.45) FURINPCSK6ALDH1A1CPB2
SCHEMBL7205366 0.84 ALDH1A1 (0.58) FURINPCSK6ALDH1A1SIRT6SIRT1
SCHEMBL30444043 0.84 ALDH1A1 (0.58) FURINPCSK6ALDH1A1SIRT6SIRT1
SCHEMBL31193414 0.84 ERAP2 (0.50) FURINPCSK6CPB2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117203217-B Polypeptide, composition and application thereof 深圳市维琪科技股份有限公司 2024-11-29 CN claimed
CN-117203217-B Polypeptide, composition and application thereof 深圳市维琪科技股份有限公司 2024-11-29 CN disclosed