SCHEMBL30608459

SCHEMBL30608459

CC(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)O)C(C)C)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FURIN P09958 6/20 0.50
PCSK6 P29122 1/20 0.50
SIRT6 Q8N6T7 1/20 0.47
SIRT1 Q96EB6 1/20 0.47
CPA1 P15085 1/20 0.43
CPA2 P48052 1/20 0.43
CPA4 Q9UI42 1/20 0.43
CTSL P07711 1/20 0.43
GNPAT O15228 1/20 0.42
CPB2 Q96IY4 2/20 0.41
NMT2 O60551 1/20 0.41
NMT1 P30419 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29464086 0.93 SIRT6 (0.53) FURINPCSK6SIRT6SIRT1CPA1
SCHEMBL30374879 0.90 FOLH1 (0.50) FURINPCSK6SIRT6SIRT1CPA1
SCHEMBL31238543 0.90 FURIN (0.56) FURINPCSK6SIRT6SIRT1CPA1
SCHEMBL6700436 0.88 GSR (0.45) FURINPCSK6CTSLCPB2NMT2
SCHEMBL6700441 0.88 GSR (0.45) FURINPCSK6CTSLCPB2NMT2
SCHEMBL29400666 0.88 FURIN (0.49) FURINPCSK6SIRT6SIRT1CPA1
SCHEMBL13811923 0.86 SIRT6 (0.52) FURINPCSK6SIRT6SIRT1CPA1
SCHEMBL29784947 0.85 NMT1 (0.48) FURINPCSK6CTSLCPB2NMT2
SCHEMBL29630488 0.84 FOLH1 (0.47) FURINPCSK6CTSLCPB2NMT2
SCHEMBL29510666 0.84 GNPAT (0.52) FURINPCSK6SIRT6SIRT1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023184114-A1 POLYPEPTIDE AND COSMETIC COMPOSITION OR PHARMACEUTICAL COMPOSITION AND USE THEREOF 深圳市维琪科技股份有限公司 2023-10-05 WO disclosed