Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.55 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27631818 | 0.75 | DAO (0.50) | HRH4DRD3DRD2LMNATSHR | |
| SCHEMBL4036808 | 0.73 | DAO (0.51) | HRH4DRD3DRD2ALDH1A1DAO | |
| SCHEMBL4039329 | 0.73 | ATAD2 (0.49) | HRH4DRD3LMNAALDH1A1DAO | |
| SCHEMBL4039658 | 0.72 | DAO (0.50) | HRH4DRD3DRD2ALDH1A1DAO | |
| SCHEMBL21590285 | 0.68 | GAA (0.57) | LMNAALDH1A1 | |
| SCHEMBL3092620 | 0.67 | ATAD2 (0.53) | HRH4DRD3ALDH1A1DAOATAD2 | |
| SCHEMBL27738193 | 0.66 | DAO (0.51) | HRH4LMNAALDH1A1CYP1A2DAO | |
| Hydrochloric Acid SCHEMBL29849575 | 0.65 | KMT2A (0.52) | LMNAALDH1A1 | |
| SCHEMBL9379906 | 0.63 | ATAD2 (0.49) | HRH4DRD3LMNADAOATAD2 | |
| SCHEMBL30568660 | 0.62 | HSD17B10 (0.54) | HRH4LMNAUSP2ALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709383-A1 | INVERSE AGONISTS OF RAR RELATED ORPHAN RECEPTORS (RORS) | 11949098 Canada Inc. (CA) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024229569-A1 | INVERSE AGONISTS OF RAR RELATED ORPHAN RECEPTORS (RORS) | 11949098 CANADA INC. (CA) | 2024-11-14 | — | — | WO | disclosed |