Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 8/20 | 0.63 |
| ▸ | JAK1 | P23458 | 5/20 | 0.63 |
| ▸ | CDK7 | P50613 | 7/20 | 0.54 |
| ▸ | ULK1 | O75385 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686431 | 1.00 | JAK2 (0.63) | JAK2JAK1CDK7ULK1DYRK1A | |
| SCHEMBL31240407 | 0.90 | JAK2 (0.63) | JAK2JAK1CDK7ULK1DYRK1A | |
| SCHEMBL26686340 | 0.87 | JAK2 (0.56) | JAK2JAK1ULK1DYRK1A | |
| SCHEMBL26686370 | 0.86 | JAK2 (0.61) | JAK2JAK1ULK1DYRK1AKIT | |
| SCHEMBL31420124 | 0.86 | JAK2 (0.61) | JAK2JAK1ULK1DYRK1AKIT | |
| SCHEMBL26685861 | 0.85 | JAK2 (0.56) | JAK2JAK1DYRK1AKITFLT3 | |
| SCHEMBL30633352 | 0.85 | JAK2 (0.56) | JAK2JAK1DYRK1AKITFLT3 | |
| SCHEMBL31240493 | 0.84 | WNT3A (0.57) | JAK2DYRK1A | |
| SCHEMBL31240431 | 0.83 | NPC1 (0.48) | JAK2JAK1ULK1DYRK1AMAPK10 | |
| SCHEMBL30633307 | 0.82 | MAPK1 (0.59) | JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |