Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 17/20 | 0.52 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | CLK3 | P49761 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240589 | 0.84 | TBK1 (0.60) | TBK1CLK2CLK3DYRK1A | |
| SCHEMBL31240533 | 0.84 | TBK1 (0.54) | TBK1LRRK2 | |
| SCHEMBL31240485 | 0.84 | TBK1 (0.54) | TBK1LRRK2 | |
| SCHEMBL31240683 | 0.80 | DYRK1A (0.54) | CLK2CLK3DYRK1A | |
| SCHEMBL31240247 | 0.79 | JAK2 (0.67) | TBK1CSF1R | |
| SCHEMBL31240352 | 0.79 | TBK1 (0.61) | TBK1CLK2CLK3DYRK1ACSF1R | |
| SCHEMBL31240700 | 0.78 | CLK2 (0.58) | TBK1CLK2CLK3DYRK1A | |
| SCHEMBL31240486 | 0.77 | CLK2 (0.55) | CLK2CLK3DYRK1A | |
| SCHEMBL26686381 | 0.77 | JAK2 (0.60) | TBK1DYRK1A | |
| SCHEMBL31240681 | 0.77 | CDK9 (0.50) | TBK1CSF1RLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |