Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 9/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.44 |
| ▸ | CLK3 | P49761 | 7/20 | 0.44 |
| ▸ | EGFR | P00533 | 7/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240389 | 0.86 | CLK2 (0.42) | CLK2DYRK1ACLK3EGFRJAK2 | |
| SCHEMBL31240648 | 0.85 | TRPA1 (0.41) | CLK2DYRK1ACLK3EGFRMAPK14 | |
| SCHEMBL31240412 | 0.85 | CLK2 (0.51) | CLK2DYRK1ACLK3EGFRMAPK14 | |
| SCHEMBL31240570 | 0.83 | DYRK1A (0.48) | CLK2DYRK1ACLK3EGFRJAK2 | |
| SCHEMBL31240504 | 0.83 | DYRK1A (0.40) | CLK2DYRK1ACLK3MAPK14WNT1 | |
| SCHEMBL31240490 | 0.81 | CLK2 (0.47) | CLK2DYRK1ACLK3EGFRMAPK14 | |
| SCHEMBL26685816 | 0.81 | JAK2 (0.47) | CLK2DYRK1ACLK3JAK2JAK1 | |
| SCHEMBL31240594 | 0.81 | DYRK1A (0.44) | CLK2DYRK1ACLK3EGFRMAPK14 | |
| SCHEMBL31240405 | 0.80 | CLK2 (0.59) | CLK2DYRK1ACLK3EGFRMAPK14 | |
| SCHEMBL31240586 | 0.80 | CLK2 (0.52) | CLK2DYRK1ACLK3EGFRJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |