Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.50 |
| ▸ | CCKBR | P32239 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 4/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | F11 | P03951 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BUB1 | O43683 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 2/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240493 | 0.90 | WNT3A (0.57) | TTKCCKBRJAK2GSK3BF11 | |
| SCHEMBL26686121 | 0.86 | MAPK1 (0.51) | JAK2F11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30633290 | 0.86 | MAPK1 (0.51) | JAK2F11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30633307 | 0.84 | MAPK1 (0.59) | JAK2F11CDC7CCNE1CDK2 | |
| SCHEMBL26685951 | 0.84 | MAPK1 (0.59) | JAK2F11CDC7CCNE1CDK2 | |
| SCHEMBL31240445 | 0.83 | WNT3A (0.47) | TTKJAK2F11RAB9AMAPK14 | |
| SCHEMBL26686340 | 0.82 | JAK2 (0.56) | JAK2GSK3AF11JAK1CDC7 | |
| SCHEMBL31240563 | 0.82 | DYRK1A (0.51) | JAK2GSK3BWNT3APIK3C3WNT1 | |
| SCHEMBL31240716 | 0.82 | JAK2 (0.54) | JAK2GSK3BGSK3AF11MAPK14 | |
| SCHEMBL31240484 | 0.82 | JAK2 (0.63) | JAK2MAPK8MAPK10JAK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |