Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.45 |
| ▸ | ULK1 | O75385 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 4/20 | 0.44 |
| ▸ | JAK1 | P23458 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 5/20 | 0.43 |
| ▸ | BCR | P11274 | 5/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240431 | 0.86 | NPC1 (0.48) | ROCK2ROCK1ULK1JAK2JAK1 | |
| SCHEMBL31240611 | 0.86 | ROCK1 (0.53) | ROCK1ULK1JAK2JAK1LRRK2 | |
| SCHEMBL31240612 | 0.86 | ROCK1 (0.53) | ROCK1ULK1JAK2JAK1LRRK2 | |
| SCHEMBL31240407 | 0.82 | JAK2 (0.63) | ULK1JAK2JAK1LRRK2ABL1 | |
| SCHEMBL31240287 | 0.82 | TP53 (0.52) | ROCK2ROCK1JAK2LIMK1 | |
| SCHEMBL26686173 | 0.81 | MAPK1 (0.56) | ROCK2ROCK1JAK2MAPK1LIMK1 | |
| SCHEMBL30633349 | 0.81 | MAPK1 (0.56) | ROCK2ROCK1JAK2MAPK1LIMK1 | |
| SCHEMBL31240361 | 0.81 | JAK2 (0.47) | ROCK2ROCK1JAK2LRRK2LIMK1 | |
| SCHEMBL31240424 | 0.79 | JAK2 (0.50) | ROCK2ROCK1JAK2LRRK2LIMK1 | |
| SCHEMBL31240461 | 0.79 | JAK2 (0.52) | ROCK2ROCK1ULK1JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |