Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 12/20 | 0.56 |
| ▸ | CDC7 | O00311 | 2/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | CDK9 | P50750 | 2/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240630 | 0.77 | CDC7 (0.52) | CDC7PIM1CDK9CCNB2CDK1 | |
| SCHEMBL31240784 | 0.77 | TBK1 (0.53) | TBK1CDC7PIM1CDK9NUDT1 | |
| SCHEMBL31240559 | 0.75 | TBK1 (0.58) | TBK1 | |
| SCHEMBL31240691 | 0.74 | CDK9 (0.52) | CDC7PIM1CDK9CCNB2CDK1 | |
| SCHEMBL17289774 | 0.72 | TBK1 (1.00) | TBK1 | |
| SCHEMBL17306356 | 0.72 | TBK1 (0.82) | TBK1CDC7PIM1CDK9 | |
| SCHEMBL31240848 | 0.72 | CDC7 (0.59) | CDC7PIM1CDK9CCNB2CDK1 | |
| SCHEMBL16041244 | 0.72 | CDC7 (0.59) | CDC7PIM1CDK9CCNB2CDK1 | |
| SCHEMBL31240593 | 0.72 | CDC7 (0.59) | CDC7PIM1CDK9CCNB2CDK1 | |
| SCHEMBL31240779 | 0.72 | CDK9 (0.47) | CDC7PIM1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |