Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.50 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 3/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240538 | 0.90 | DYRK1A (0.52) | DYRK1AWNT3ARIOK2NR3C2CYP2D6 | |
| SCHEMBL31240240 | 0.89 | MAPK14 (0.55) | MAPK14GSK3BWNT3AJAK2CDK1 | |
| SCHEMBL31240675 | 0.89 | WNT3A (0.52) | MAPK14WNT3ARIOK2JAK2CDK1 | |
| SCHEMBL31240509 | 0.89 | JAK2 (0.56) | MAPK14GSK3BDYRK1AWNT3AJAK2 | |
| SCHEMBL31240714 | 0.87 | WNT3A (0.55) | MAPK14WNT3ARIOK2JAK2CDK1 | |
| SCHEMBL31240349 | 0.87 | WNT3A (0.50) | MAPK14WNT3ARIOK2MAPK1JAK2 | |
| SCHEMBL31240493 | 0.87 | WNT3A (0.57) | MAPK14GSK3BDYRK1AWNT3ARIOK2 | |
| SCHEMBL31240322 | 0.85 | MAPK10 (0.58) | WNT3ARIOK2NR3C2CDK2 | |
| SCHEMBL31240457 | 0.85 | WNT3A (0.50) | MAPK14GSK3BWNT3ARIOK2JAK2 | |
| SCHEMBL31240732 | 0.84 | JAK2 (0.51) | MAPK14DYRK1AMAPK1JAK2CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |