Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 3/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.35 |
| ▸ | CDK1 | P06493 | 3/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240691 | 0.90 | CDK9 (0.52) | CDK9CDC7PIM1EGFRMAPK14 | |
| SCHEMBL31240630 | 0.82 | CDC7 (0.52) | CDK9CDC7PIM1AXLPRKCI | |
| SCHEMBL31240799 | 0.80 | CDK9 (0.42) | CDK9CDC7PIM1EGFRMAPK14 | |
| SCHEMBL31240636 | 0.76 | CDK9 (0.40) | CDK9CDC7PIM1EGFRMAPK14 | |
| SCHEMBL31240664 | 0.75 | CDK9 (0.48) | CDK9CDC7PIM1EGFRMAPK14 | |
| SCHEMBL31240595 | 0.74 | CDK1 (0.49) | CDK9CDC7PIM1MAPK14RIPK1 | |
| SCHEMBL16041244 | 0.74 | CDC7 (0.59) | CDK9CDC7PIM1EGFRMAPK14 | |
| SCHEMBL31240848 | 0.74 | CDC7 (0.59) | CDK9CDC7PIM1EGFRMAPK14 | |
| SCHEMBL31240593 | 0.74 | CDC7 (0.59) | CDK9CDC7PIM1EGFRMAPK14 | |
| SCHEMBL31240779 | 0.74 | CDK9 (0.47) | CDK9CDC7PIM1AXLPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |