Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 6/20 | 0.42 |
| ▸ | CDC7 | O00311 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 4/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | PRKX | P51817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240691 | 0.83 | CDK9 (0.52) | CDK9CDC7PIM1EGFRMAPK14 | |
| SCHEMBL31240636 | 0.83 | CDK9 (0.40) | CDK9CDC7PIM1PTK2EGFR | |
| SCHEMBL31240355 | 0.80 | CDK9 (0.41) | CDK9CDC7PIM1CYP2D6CCNT1 | |
| SCHEMBL31240785 | 0.80 | CDK9 (0.47) | CDK9CDC7PIM1EGFRMAPK14 | |
| SCHEMBL31240389 | 0.77 | CLK2 (0.42) | EGFRCLK2JAK3DYRK1A | |
| SCHEMBL31240722 | 0.77 | CDK9 (0.56) | CDK9CDC7PIM1CDK2CCNT1 | |
| SCHEMBL31240630 | 0.75 | CDC7 (0.52) | CDK9CDC7PIM1GSK3BCDK5 | |
| SCHEMBL26889101 | 0.73 | AXL (0.40) | CDK9CDC7PIM1CYP1A2CYP2C8 | |
| SCHEMBL1777011 | 0.71 | CDC7 (0.56) | CDK9CDC7PIM1GSK3BCDK5 | |
| SCHEMBL31240664 | 0.69 | CDK9 (0.48) | CDK9CDC7PIM1EGFRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |