SCHEMBL3124267

SCHEMBL3124267

CCCCCCCCCCCCCCCCCCNC(CCO)CCO

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.44
ALDH1A1 P00352 3/20 0.44
TSHR P16473 2/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
NAAA Q02083 1/20 0.42
KDM4E B2RXH2 2/20 0.41
EPHX1 P07099 8/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
CNR1 P21554 1/20 0.38
ADRA1A P35348 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2567393 1.00 LMNA (0.44) LMNAALDH1A1TSHRHSD17B10MEN1
Hydrochloric Acid SCHEMBL5353822 0.98 LMNA (0.42) LMNAALDH1A1TSHRHSD17B10MEN1
Hydrochloric Acid SCHEMBL1804687 0.98 LMNA (0.42) LMNAALDH1A1TSHRHSD17B10MEN1
Bromide SCHEMBL10985393 0.98 LMNA (0.42) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL12521850 0.98 SMN1; SMN2 (0.42) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL16628432 0.94 EPHX1 (0.39) LMNAALDH1A1TSHRHSD17B10MEN1
Fluoride SCHEMBL9760387 0.89 RRM1 (0.45) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL7623261 0.89 ALDH1A1 (0.53) ALDH1A1MEN1KMT2AKDM4ECNR1
SCHEMBL2999471 0.89 ALDH1A1 (0.53) ALDH1A1MEN1KMT2AKDM4ECNR1
SCHEMBL28675328 0.88 LMNA (0.43) LMNAALDH1A1TSHRHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170253787-A1 COMPLEX EMULSIFIER COMPOSITIONS AND METHODS OF USE M-I L.L.C. 2017-09-07 US disclosed
US-8865833-B2 Polycarbonate composition comprising nanomaterials SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2014-10-21 US disclosed
US-20100280176-A1 POLYCARBONATE COMPOSITION COMPRISING NANOMATERIALS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-11-04 US disclosed
WO-2008091413-A2 POLYCARBONATE COMPOSITION COMPRISING NANOMATERIALS SABIC INNOVATIVE PLASTICS BV (US) 2008-07-31 WO disclosed
US-20080167414-A1 a nanocomposite mixture of aromatic polycarbonates and silica, clays, talc or alumina nanostructure particles, used in the preparation of articles by injection molding or extrusion CITIBANK, N.A., AS COLLATERAL AGENT 2008-07-10 US disclosed
WO-2008042496-A1 METHOD OF MAKING POLYCARBONATE NANOCOMPOSITES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-04-10 WO disclosed
US-20080081865-A1 METHOD OF MAKING POLYCARBONATE NANOCOMPOSITES CITIBANK, N.A., AS COLLATERAL AGENT 2008-04-03 US disclosed
US-20070004842-A1 Polymer nanocomposite blends TOMOVA DANIELA 2007-01-04 US disclosed
US-6548587-B1 Nanocomposites, bottles; poly-m-xylylene adipamide and quaternized montmorillonite clay UNIVERSITY OF SOUTH CAROLINA RESEARCH FOUNDATION 2003-04-15 US disclosed