Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 9/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14489414 | 0.91 | VDR (0.51) | VDRADRA1ANR1I2PGRHTR1A | |
| SCHEMBL7156998 | 0.86 | VDR (0.62) | VDRADRA1ANR1I2PGRHTR1A | |
| SCHEMBL14489178 | 0.86 | VDR (0.62) | VDRADRA1ANR1I2PGRHTR1A | |
| SCHEMBL67842 | 0.85 | VDR (0.64) | VDRADRA1ANR1I2PGRHTR1A | |
| SCHEMBL14364796 | 0.85 | VDR (0.64) | VDRADRA1ANR1I2PGRHTR1A | |
| SCHEMBL14364795 | 0.85 | VDR (0.64) | VDRADRA1ANR1I2PGRHTR1A | |
| SCHEMBL14415914 | 0.85 | VDR (0.64) | VDRADRA1ANR1I2PGRHTR1A | |
| SCHEMBL67867 | 0.85 | VDR (0.64) | VDRADRA1ANR1I2PGRHTR1A | |
| SCHEMBL2468787 | 0.85 | VDR (0.64) | VDRADRA1ANR1I2PGRHTR1A | |
| SCHEMBL68416 | 0.85 | VDR (0.64) | VDRADRA1ANR1I2PGRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829746-B2 | Process for the preparation of calcipotriol | INSTYTUT FARMACEUTYCZNY (PL) | 2010-11-09 | — | — | US | disclosed |
| US-20100222614-A1 | PROCESS FOR THE PREPARATION OF CALCIPOTRIOL | INSTYTUT FARMACEUTYCZNY (PL) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222614-A1 | PROCESS FOR THE PREPARATION OF CALCIPOTRIOL | CYP2R1, CYP24A1, DHCR24 | VDR 4/4885ADRA1A 932/4885NR1I2 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.