Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11949323 | 0.81 | RORC (0.55) | OPRL1RORCSIGMAR1 | |
| SCHEMBL31252999 | 0.79 | RORC (0.51) | OPRL1RORCSIGMAR1 | |
| SCHEMBL1807709 | 0.78 | OPRL1 (0.53) | OPRL1RORCSIGMAR1 | |
| SCHEMBL31387362 | 0.76 | RORC (0.51) | OPRL1RORCSIGMAR1 | |
| SCHEMBL1805405 | 0.74 | RORC (0.48) | OPRL1RORCSIGMAR1 | |
| SCHEMBL31593978 | 0.71 | RORC (0.47) | OPRL1RORCSIGMAR1 | |
| SCHEMBL30484456 | 0.70 | RORC (0.52) | OPRL1RORCSIGMAR1 | |
| SCHEMBL18579655 | 0.69 | OPRL1 (0.45) | OPRL1RORCSIGMAR1 | |
| SCHEMBL25359159 | 0.69 | OPRL1 (0.47) | OPRL1RORCSIGMAR1 | |
| SCHEMBL1808227 | 0.69 | OPRL1 (0.45) | OPRL1RORCKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013281-A | 4',5' -Dihydrospiro [ piperidine-4, 7' -thieno [2,3-C ] pyran ] derivatives as APOL1 inhibitors and methods of use thereof | 弗特克斯药品有限公司 | 2024-11-22 | — | — | CN | disclosed |